1. |
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Introduction
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Introduction to Molecular Biology -Syllabus - Historical Background. |
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2. |
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Macromolecules
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Proteins, Nucleic acid, polysaccharide, and lipid.
Structure and Function of macromolecules. |
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3. |
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Structure of Macromolecules: nucleic acid
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Structure and Function of Proteins.
Structure and Function of Nucleic acids - On the biological membrane. |
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4. |
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Genetic Material
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Experimental evidances that DNA is the Genetic material. Characteristics of Genetic material. |
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5. |
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DNA Replication
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Basic mechanism of DNA.
Enzymologies for DNA replication. |
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6. |
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Mutageneis
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Types of mutagenesis. Spontaneous mutagenesis and induced mutagenesis. Ames test. |
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7. |
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DNA Repair
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types of DNA repair. Direct repair. Excision repair, SOS repair. |
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8. |
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Transcription
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RNA polymerase. Elements for transcription. Stages of Transcription. |
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9. |
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Gene Expression(1)
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concepts for gene expression.
diauxic growth curve.one the lac operon. |
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10. |
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Gene Expression(2)
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operon.arabinose operon.trp operon. |
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11. |
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Translation(1); Protein synthesis
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Elements for translation.Genetic
code. Characteristics of genetic code. |
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12. |
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Translation(2); Protein synthesis
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Elements for translation. mRNA. ribosome . tRNA .amino acids. |
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13. |
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Translation(3); Protein synthesis
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Stages of translation. initiation; SD sequence, P site, A-site, fMet-tRNA, IFs - elongation; transpeptidation, translocation, G-protein, EFs - termination; stop codons, RFs, RRF |
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14. |
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Genomics and Applications of gene manipulation
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Introduction to Genomics - Overview of gene manipulation.Applications of genetic engineering. |
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