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2. Introduction to drugtargets and molecularpharmacology | Pharmacology introduction, The nature of drug targets | ![]() |
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2. Introduction to drugtargets and molecularpharmacology | Pharmacology introduction, The nature of drug targets | ![]() |
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3. Molecular cloning of drug targets | The relevance of recombinant DNA technology to pharmacology/drug discovery | ![]() |
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Molecular cloning of drug targets, Agonist selectivity | The cloning of drug targets | ![]() |
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Agonist selectivity, Affinity, Efficacy | Agonist selectivity, Affinity, Efficacy | ![]() |
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Efficacy, Drugs with multiple efficacies, Quantifying agonist activity, Bi-Molecular Systems, What is drug antagonism | Efficacy, Drugs with multiple efficacies, Quantifying agonist activity, Bi-Molecular Systems, What is drug antagonism | ![]() |
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What is drug antagonism, Antagonist potency, Mechanism of receptor antagonism, Competitive and non-competitive antagonism | What is drug antagonism, Antagonist potency, Mechanism of receptor antagonism, Competitive and non-competitive antagonism | ![]() |
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Orthosteric antagonist,Competitive and non-competitive antagonism | Orthosteric antagonist,Competitive and non-competitive antagonism | ![]() |
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Characteristic properites of allosteric molecules and how they interact with proteins | 1. Introduction 2. protein allosterism 3. types of allosteric modulators 4. Unique effects of allosteric modulators 5. Detecting allosterism 6. Summary | ![]() |
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Introduction to molecularpharmacology, G-protein coupled receptors | G-protein coupled receptors, Ion channels | ![]() |
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Ion Channels, Nuclear receptors, Transporters | Ion Channels, Nuclear receptors, Transporters | ![]() |
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Molecular Pharmacology | GPCR | ![]() |
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Molecular Pharmacology | GPCR | ![]() |
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Signal transduction pathway, Desensitization and down-regulation of GPCR signaling, Constitutive GPCR activity | Signal transduction pathway, Desensitization and down-regulation of GPCR signaling, Constitutive GPCR activity | ![]() |
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Promiscuous G protein coupling, Agonist-directed signalling, Allosteric modulators of GPCR function, Pharmacological chaperones for GPCRs | Promiscuous G protein coupling, Agonist-directed signalling, Allosteric modulators of GPCR function, Pharmacological chaperones for GPCRs | ![]() |
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Pharmacological chaperones for GPCRs, GPCR dimerization, GPCR splice variants | Pharmacological chaperones for GPCRs, GPCR dimerization, GPCR splice variants | ![]() |
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GPCR dimerization | Methods to study GPCR dimerzation, Homodimerization, Heterodimerization | ![]() |
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Class C GPCR | Class C GPCR | ![]() |
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GPCR splice variants have an influence on GPCR pharmacology | GPCR splice variants have an influence on GPCR pharmacology | ![]() |
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GPCR drug examples, Voltage-gated ion channels | GPCR drug examples, Voltage-gated ion channels | ![]() |
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Voltage-gated ion channels | Voltage-gated ion channels | ![]() |
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Voltage-gated ion channels, Ligand-gated ion channels | Voltage-gated ion channels, Ligand-gated ion channels | ![]() |
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Ligand-gated ion channels | Ligand-gated ion channels | ![]() |