Brain Science Fundamentals

한국과학기술원
Christopher Fiorillo

페이스북 트위터 카카오톡 네이버밴드 링크복사

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자연과학 >생물ㆍ화학ㆍ환경 >생명과학
강의학기

2012년 가을학기

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This course is intended to serve as an introduction to neuroscience. The typical approach to teaching an introductory neuroscience course is to focus almost exclusively on the mechanics of brain function (the biophysical mechanisms by which molecules and cells interact in the brain). This course will cover basic biophysical mechanisms at all levels from molecules to neurons to neural systems. However, in addition, this course will cover theoretical aspects of information processing and how information processing relates to both the mechanics of the nervous system and the system’s general computational goals.

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Introduction

차시별 강의

1.	Introduction	1. Introduction of this course 2. Overview of mechanics
	Introduction	1. Introduction of this course 2. Overview of mechanics
2.	The Goal of the Brain	1. Function of Brain 2. Information, probability and prediction
	The Goal of the Brain	1. Function of Brain 2. Information, probability and prediction
3.	Overview of Function	1. Information flows through molecular sensors 2. Information transformation in sensory-motor pathway
	Overview of Function	1. Information flows through molecular sensors 2. Information transformation in sensory-motor pathway
4.	Overview of Structure	1.Structure of neurons 2. Classifying neurons
	Overview of Structure	1. Structure of neurons 2. Classifying neurons
5.	Membrane voltage : passive properties(1)	1. properties of water, ion, and neuronal membrane 2. ion channels, equilibrium potential and resting potential
	Membrane voltage : passive properties(1)	1. properties of water, ion, and neuronal membrane 2. ion channels, equilibrium potential and resting potential
	Membrane voltage : passive properties(2)	1. an equivalent circuit of neuronal membrane 2. common features of ion channels 3. function of action potential
6.	Membrane voltage : active properties(1)	1. patch clamp recording 2. action potential and voltage gated ion channel
	Membrane voltage : active properties(1)	1. patch clamp recording 2. action potential and voltage gated ion channel
	Membrane voltage : active properties(2)	1. Hodgkin-Huxley model and action potential conduction 2. Ion channel diversity
	Membrane voltage : active properties(3)	1. Three Key Properties of Voltagegated Ion Channels 2. Conduction velocity
7.	Voltage-Regulated Channels	1. Functional Classification of Ion Channels 2. Maintaining Homeostasis
	Voltage-Regulated Channels	1. Functional Classification of Ion Channels 2. Maintaining Homeostasis
8.	Synapse (1)	1. synaptic transmission and release probability 2. paired pulse depression and facilitation
	Synapse (2)	1. synaptic transmission and release probability 2. paired pulse depression and facilitation
	Synapse	1. synaptic transmission and release probability 2. paired pulse depression and facilitation
9.	Neurotansmitters, Receptors, and Signal Transduction (1)	1. Dale s principle 2. Types of neurotransmitter
	Neurotansmitters, Receptors, and Signal Transduction (2)	1. Receptors : ionotropic receptor, metabotropic receptor 2. G protein and second messenger
	Neurotansmitters, Receptors, and Signal Transduction
10.	Gross Anatomy of the Brain (1)	1. Anatomical terms
	Gross Anatomy of the Brain (2)	2. major division of CNS and cortex, and brodmann map
	Gross Anatomy of the Brain	1. Anatomical terms 2. major division of CNS and cortex, and brodmann map
11.	Theory of learning (1)	1. input and output of a neuron
	Theory of learning (2)	2. Hebbian and anti-hebbian plasticity
	Theory of learning	1. input and output of a neuron 2. Hebbian and anti-hebbian plasticity
12.	Development of Connectivity (1)	1. Development of neuronal structure
	Development of Connectivity (2)	2. Synaptic rearrangement in LGN and visual cortex
	Development of Connectivity	1. Development of neuronal structure 2. Synaptic rearrangement in LGN and visual cortex
13.	Mechanisms of Learning (1)	1. Model for the study of associative plasticity : hippocampus 2. Glutamate receptors 3. Long term potentiation and depression(LTP, LTD)
	Mechanisms of Learning (2)	1. Habituation and Sensitization of Gill-Withdrawal Reflex 2. Classical conditioning in Aplysia 3. Synaptic timing dependent plasticity(STDP)
	Mechanisms of Learning	Mechanisms of learning and plasticity in neurons